It's the height of the Palm Beach charity ball season: for every good cause, there's a reason for the local luminaries to eat (minimally), drink (maximally), and be seen. But when prominent high-society dowager Kiki Pew suddenly vanishes during a swanky gala, and is later found dead, panic and chaos erupt.
Kiki was an ardent fan of the Winter White House resident just down the road, and a founding member of the POTUSSIES, a group of women dedicated to supporting their President - who immediately declares that Kiki was the victim of rampaging immigrant hordes. This, it turns out, is far from the truth.
The truth might just lie in the middle of the highway, where a bizarre discovery brings the First Lady's motorcade to a grinding halt. Enter Angie Armstrong, wildlife wrangler extraordinaire, who is summoned to the posh island to deal with a mysterious and impolite influx of huge, hungry pythons . . .